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Quantification of Proteolytic Pathways in MCF7 Breast Cancer Cells

Quantification of Proteolytic Pathways in MCF7 Breast Cancer Cells

  • 2/11/2019 8:30:00 AM
  • View Count 1682
Jessica Cardin, PhDProtein degradation is a main component of the body to enable proper function and tissue maintenance. Certain types of cancer have demonstrated to have an enhanced ability to degrade malformed proteins through intracellular systems. The ability to break these proteins down has the potential to protect cancerous cells and allow them to proliferate. Specific degradation pathways have exhibited the capacity to alter the cell cycle, leading to tumors to increase in aggressiveness ...
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"Unpacking" Muscles

"Unpacking" Muscles

  • 4/8/2018 10:00:00 AM
  • View Count 1931
Jessica Cardin, M.S.Skeletal muscle has a high degree of plasticity that allows the tissue to respond to environmental cues (exercise, disuse, starvation, etc.). The majority of research has focused on the building of muscle. However, atrophy has vast implications across many disease states (cancer cachexia, renal failure, COPD, and Type II Diabetes). The understanding of how atrophy occurs as an "unpacking" process of the muscle fiber is limited. Pioneering research is important as it...
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