Jacqueline I. Perticone, B.S.Loss of muscle mass with advancing age, disease or lifestyle has a profound influence on healthcare and society. Our laboratory uses hindlimb suspension in rodents to better understand loss of muscle mass occurring with disuse in an effort to design specific interventions that may be suitable to maintain muscle health and function in a number of populations. It is well-known that loss of muscle mass with reduced activity results from a slowdown in the muscle’s ...

Kevin Shimkus, B.S.In muscle research, we tend to pay a great deal of attention to a particular signaling protein called mTOR, a key regulatory protein that signals for cell growth through the creation of new proteins. Consider protein building similar to a race car. The larger the engine, the greater potential for speed. Similarly, the more mTOR protein present in any given cell, the greater potential for more protein construction. And just like the gas pedal fuels the engine, mTOR is a signali...

Andrew Jagim, Ph.D, CSCSIt makes sense right? It’s the day after a tough workout, you’re sore, it hurts to move but you have to move because you have another session with your trainer in two hours. So, what do you do? You pop some non-steroidal anti-inflammatories (NSAIDs) to take the edge off and get back out there for round 2! The question is: Is this doing more damage than good? It seems as though there has always been some controversy regarding the administration of NSAIDs. Are t...