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Powering Skeletal Muscle Growth

Powering Skeletal Muscle Growth

  • 6/25/2014 6:16:00 AM
  • View Count 3710
Jacqueline I. Perticone, B.S.Loss of muscle mass with advancing age, disease or lifestyle has a profound influence on healthcare and society. Our laboratory uses hindlimb suspension in rodents to better understand loss of muscle mass occurring with disuse in an effort to design specific interventions that may be suitable to maintain muscle health and function in a number of populations. It is well-known that loss of muscle mass with reduced activity results from a slowdown in the muscle’s ...
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Understanding mTOR: Great for Muscle, Bad for Cancer

Understanding mTOR: Great for Muscle, Bad for Cancer

  • 6/18/2014 12:02:00 PM
  • View Count 13187
Kevin Shimkus, B.S.In muscle research, we tend to pay a great deal of attention to a particular signaling protein called mTOR, a key regulatory protein that signals for cell growth through the creation of new proteins. Consider protein building similar to a race car. The larger the engine, the greater potential for speed. Similarly, the more mTOR protein present in any given cell, the greater potential for more protein construction. And just like the gas pedal fuels the engine, mTOR is a signali...
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What if I Want My Inflammation? -- The Effects of NSAIDs on Training Adaptations

What if I Want My Inflammation? -- The Effects of NSAIDs on Training Adaptations

  • 5/21/2013 10:32:00 AM
  • View Count 3192
Andrew Jagim, Ph.D, CSCSIt makes sense right? It’s the day after a tough workout, you’re sore, it hurts to move but you have to move because you have another session with your trainer in two hours. So, what do you do? You pop some non-steroidal anti-inflammatories (NSAIDs) to take the edge off and get back out there for round 2! The question is: Is this doing more damage than good? It seems as though there has always been some controversy regarding the administration of NSAIDs. Are t...
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Mighty Mouse: Understanding Myostatin

Mighty Mouse: Understanding Myostatin

  • 9/17/2012 10:06:00 AM
  • View Count 7113
Kevin Shimkus, B.S.As is well known, physical gains become slower and more difficult to achieve as athletes reach a more elite status.  For those involved in strength- and power-based sports, improvements in strength and mass eventually plateau, and even rigorous workout and nutritional prescriptions may yield only minimal increases.  So it is little surprise that many in the athletic world are starting to pay more attention to some very special mice.      &nbs...
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